Candidacy Vaccine for Medical Countermeasure of Novel Coronavirus, Ribonitrogensic_Riboviral

Coronavirus are important agents of gastrointestinal diseases in humans and animals. In human, a species known as SARS, Severe Acute Respiratory Syndrome coronaviruses causes highly contagious respiratory diseases. In 2012, another coronavirus capable of causing a severe acute respiratory diseases later known as Middle East Respiratory Syndrome coronavirus, (MERS-Cov) was discovered in humans. The first case was discovered in Saudi-Arabia. The Middle East Respiratory Syndrome Coronavirus (MERS-Cov) is a life-threatening respiratory diseases with a high case fatality rate. In the late December 2019, a virus apparently closely related to SARS Coronavirus emerged in Wuhan China. The Wuhan Coronavirus caused an illness similar to SARS, Characterized by Fever and Respiratory Symptoms. The coronavirus was named Novel Coronavirus and codenamed nCovid-19 by the World Health Organization in the early February, 2020. In this project , we are going to examined , how these coronaviruses is been introduced to the human body, Lysogenic Effect of these Coronaviruses , Cytopathic Effect of these Coronaviruses , Inclusion Bodies of these Coronaviruses, Heat-Resistances of these Coronaviruses ,Disinfectant-Resistance of these Coronaviruses , Acidity and Alkality of the Coronaviruses, Modification of the Coronaviruses , Toxicity of these coronaviruses in air , water and Human Body .Causes of these Coronaviruses , Medical Countermeasures, Drug Development, antiviral Vaccines for the Coronaviruses, to be named , Ribonitrogensic_Riboviral , RRb. Laboratory preparation of Ribonitrogensic_Riboviral . Detail Description of the Ribonitrogensic_Riboviral, Stoichiometry analysis details of the Ribonitrogensic_Riboviral ,Pharmaceutical Composition of the Vaccines, Ribonitrogensic_Riboviral, RRb, Toxicology effect of the Vaccine , Ribonitrogensic_Riboviral, RRb, Health Hazardous , Experimental Design of the production of the Vaccines, Ribonitrogensic_Riboviral, RRb, The Side Effect of the Vaccine , Ribonitrogensic _Riboviral, RRb, Uses of the Vaccines, Ribonitrogensic_Riboviral, RRb, Economic Importance of the Vaccine to the world , Structural Designed of the Vaccine , Ribonitrogensic_Riboviral, RRb, , Recommendation , Result and Conclusion . The Medical countermeasure for the novel coronavirus n covid-19, will be named Ribonitrogensic Riboviral Ribonitrogensic Riboviral, RRB coded named from the intermediate of the component of the anti-virus vaccine formed .The spectator ions, which actually take part in the formation of these vaccine, oxide of nitrogen, and the RNA molecules developed for medical counter measure of these virus. On these account, we named the vaccines as Ribonitrogensic Riboviral, RRB. When Ribonitrogensic Riboviral is administer as a vaccine either injection or injection, it breaks and damage the active cells in the nCovid -19 that causes the shrinking or swallowing of the respiratory trait of the human, it also aids the flow of blood from the lung to the other parts of the body, and the potential enriches the tissues of the respiratory tract and repairs the worn out tissues. However, some references indicate that Nitrogen can be used as Biological Disinfectant which does not have problem in Ecological Effect. This indicates that 44 % Nitrogen in the Compound of this Candidacy Vaccine shows the efficacy and Effectiveness of the Candidacy Vaccine of coronavirus, Ribonitrogensic_Riboviral .The molecule formula of the Ribonitrogensic Riboviral is C4H10N6O4. It has an approximately molecular weight of 194%/mol. Appearance of Ribonitrogensic Riboviral RRb: The color appearance of Ribonitrogensic_Riboviral is colorless in solution and white crystalline in a solid form. The RRb has a molecular weight of 194g/mol. Side Effect of Ribonitrogensic_Riboviral RRb: The literature data on the acute toxicity profile of the Ribonitrogensic_Riboviral, RRb shows, it is generally regard safe with non-teratogenic compound due to the production line of the vaccine. The ability of the Ribonitrogensic_Riboviral RRb of a generic name, B-Oxonitrogensic-5,methyl –2, amino-1,2,4- triazolecarboxylate will rapidly scavenge and disinfect the coronaviruses, such as SARS- COV, MERS, nCovid-19by chelation when it is use in severe acute animal and human studies. Vaccination dose: The dose that should be taken by the patient that affected by the coronavirus for the usage of vaccine tablet through ingestion should be 169mg/50kg of the body weight for every 4 hours for 72 hours. The dosage to be used of given through injection should be 25ml/body weight for every 4 hours for 72 hours. Result: The clinical trial animals to be used are bat, mice, monkey, rabbit. The pre-clinical trials are to be carried on those animals and the result of test of response to the administer of Ribonitrogensic_Riboviral are to be noted with four(4) different stages on group of animals and there offer to the human that have been infected with the viruses. Use of Ribonitrogensic_Riboviral, RRb 1. B-Oxonitrogenic- 5,methyl- IH-1,2,4,- triazolenitrogensiccarboxylate, Ribonitrogensic-Riboviral, RRb is mainly develop for disinfection and vaccines for cure of coronaviruses such as severe acute Respiratory, Syndrome, SARS, Middle past Respiratory Syndrome, MERS and Novel coronavirus , nCovid-19. 2. It can also be used to cure a Lassa fever when 5ml of SodaSulphanecobalamin is added to the RRb 3. It can also be used to cure other Respiratory in factious diseases. Heath Hazardous of Ribonitrogensic_Riboviral Related of Exposure: Ribonitrogensic_Riboviral does not have any effect on the Immune system of the Human it is inhaled, comes in contact in eye or with skin. Effect of over exposure: Inhalation Ingestion or skin absorption of Ribonitrogensic Riboviral cannot be fatal. Larger dose may cause the person blood pressure to be extreme lower and also leads to blood agglutination. Physical data of Ribonitrogensic_Riboviral. Molality: / 1mol/Kg. Molarity: / 1 M. Molecular Structure: Irregular tetrahedral. Molecular weight: 194&mol. Melting point: Not yet Boiling point: Not yet Solubility: Soluble in water, & propanol, methyl alcohol. Appearance: Colorless solution with pleasant odor smell. Economic Importance of the Ribonitogaensic – Riboviral: The coronavirus which causes illness of respiratory diseases, which is highly contagious and level of the fatality is high. These novel coronaviruses have causes many untimely death and also prolonged symptoms that could not be provided by medical treatment. Several agencies, research institution, giant pharmaceutical companions and government entities have not get the vaccine for medical counter measure against this deadly diseases of corona virus. The novel corona viruses 2019, nCovid–19, has crippled the economy in the world, and trillions of dollars have been lost due to the novel corona virus 2019/ nCovid – 19, and also slow down the development of some countries that have been affected. At presently more than forty countries (40) have been affected by the novel corona virus – 2019, nCovid–19, and there is sporadic spread of these viruses. This novel coronavirus have killed more than two thousand people, and close to eighty thousand people have been affected and under an intensive – care presently. These deadly bio – agent has causes so many outcry all over the world during the out breaks and created pressures to scientist and government of the affected countries. It is quintessential, and extremely important to provide the vaccine for the medical counter measures for these nCovid –19, and others corona viruses urgently to address the disastrous and catastrophic pandemonium currently in the world, and to save thousands of the affected people currently under intensive – care. It is no doubt that this vaccine, Ribonitrogensic_Riboviral will be of great economy importance to the world, will safe more than eighty thousand people affected and the future of those who will be affected for these corona viruses. The most efficient, efficacy and reliable way which will proffer long – time solution for medical counter measures for coronavirus is Ribonitrogensic_Riboviral, RRb. It is non – Carcinogenic, Non – Mutagenic / and non – Teratogenic compound/vaccine. Time – line of the production: The first production/ laboratory preparation for the vaccine, Ribonitrogensic_ Riboviral for the medical counter measures will take 1 month, 21 days non – stopping working. The subsequent vaccine production will take three (3) days and more than one thousand vaccines, Ribonitrogensic_Riboviral will be produce of 25ml / quantity. Vaccination dose: The dose that should be taken by the patient that affected by the coronavirus for the usage of vaccine tablet through ingestion should be 169mg/50kg of the body weight for every 4 hours for 72 hours. The dosage to be used if given through injection should be 25ml/body weight for every 4 hours for 72 hours. . Preclinical Studies on Animals: Different Four different species of animals are group into three group. Our Studies shows that Bat could responsible in this cause of these viruses and also aid in transmitting the virus to the Human, over Bat, a fruit-eater could also be used as an in vitro animal , other in vitro animals to be use are cat , rabbit ,and dog . Each animals will be grouped into three stages, A, B and C. The pathogen are introduced into these animals and study is been carry on careful. Upon introduced these pathogens, coronavirus in these animals, Group A animals are left in there domain without administration of the Candidate Vaccine therapeutics, Ribonitrogensic_Riboviral, RRb for more than 15 days. There should be 99 % Death of the Group A Animals, therefore, it will be confirm that these pathogens is effective and highly contagious in these group A Animals. Therefore, the Candidacy Vaccine Therapeutic, Ribonitrogensic_Riboviral can be use, and should be administer to the group B animals. The administration of the Candidacy Vaccine therapeutics, Ribonitrogensic_Riboviral will be done with an approved dosage after the Group B Animals must have been infected with the coronavirus. The Candidacy Vaccine Therapeutic, Ribonitrogensic_Riboviral should break the cell of the virus and kill the virus of the Group B, Animals that are affected with the coronaviruses. Another Dosage of the Candidacy Vaccine therapeutics is administer to the Group C, Animals, affected with the coronaviruses. The response of these Group B and Group C animals, towards the Medical Countermeasure is be noted and recorded per dosage per hour and the rate at which the viruses was damaged or killed . Group A Group B Group C Bat -------- ---------- --------- Cat -------- -------- --------- Rabbit --------- ---------- --------- Dog --------- ------------- ------------